Siemens Tissue Preparation Solution offers new use to increase molecular lab efficiency


The Siemens Tissue Preparation Solution now provides molecular pathology laboratories the ability to extract high quality nucleic acids from fresh frozen (FF) tissues as well as from formalin-fixed, paraffin embedded (FFPE) tissues. This makes it today the only fully automated solution available for standardized isolation of nucleic acids from both FFPE and FF tissue samples obtained from surgeries or biopsies for in vitro diagnosis and research.


Usually, FF tissue samples require separate workflows and specific kits not compatible with FFPE tissues, making the integration of these two processes a challenge for molecular pathology labs. Now, the consolidation of both tissue types on the Siemens Tissue Preparation Solution enables labs to fully automate workflows to further increase productivity and efficiency and enable consistent and reliable delivery of testing results.


FF tissues are typically used for quick diagnosis of patients undergoing surgery, research or tissue collection and storage. FFPE tissue samples are routinely prepared from tissues obtained from surgeries and biopsies. In clinical diagnostics, nucleic acids are extracted from these samples for use in infectious disease and oncology testing.


Before the introduction of this Siemens solution, laboratories were limited to systems that were either manual or only automated for certain steps of the process. “When compared to other manual and semi-automated procedures, the Siemens method really sets a new standard in quality and workflow efficiency for routine molecular pathology laboratories,” comments Manfred Dietel, MD, Director of Institute of Pathology, University Hospital, Charité Berlin.


The Siemens Tissue Preparation Solution includes a Tissue Preparation System¹ and Versant Tissue Preparation Reagents kit.


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The products/features (here mentioned) are not commercially available in all countries. Due to regulatory reasons their future availability cannot be guaranteed. Further details are available from the local Siemens organizations.



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1The Tissue Preparation System consists of a Hamilton MICROLAB® STARlet IVD instrument and Siemens tissue extraction software protocol.