A bibliography of clinical studies and white papers on wide-angle tomosynthesis

Aug 17, 2017

StudyYearKey findingsDownload

PMA study for FDA approval of adjunct Digital Breast Tomosynthesis



Wide-angle 2-view DBT plus 2-view FFDM is superior to 2-view FFDM alone for the screening and diagnosis of breast cancer.


White Paper
PMA studies for FDA approval of adjunct and stand-alone Digital Breast Tomosynthesis2017

Wide-angle DBT used in adjunct to FFDM or even as a stand-alone modality shows superior diagnostic accuracy, a reduced non-cancer recall rate, improved reader performance, and lower interobserver variability compared to FFDM alone.


White Paper

Endo et al. “Detectability comparison of modes in dual-mode digital breast tomosynthesis”



AUC increase with the addition of DBT is significantly higher with a wide (40°) rather than a narrow (15°) angle. This is mainly due to the wider angle and not because of e.g. higher dose.


Clinical Study

Clauser et al. “Diagnostic performance of digital breast tomosynthesis with a wide scan angle compared to full-field digital mammography for the detection and characterization of microcalcifications”


2016Wide scan-angle DBT enables the detection and characterization of microcalcifications with no significant differences from FFDM.Clinical Study

Goodsitt et al. “Digital breast tomosynthesis: Studies of the effects of acquisition geometry on contrast-to-noise ratio and observer preference of low-contrast objects in breast phantom images”


2015Images acquired with wide tomosynthesis angles have higher CNR and are preferred by readers over those acquired with narrow angles.Clinical Study

Dance et al. “Comparison of breast doses for digital tomosynthesis estimated from patient exposures and using PMMA breast phantoms”


2012Dose for tomosynthesis with the wide-angle Siemens Mammomat Inspiration system is lower than with systems of other vendors.Clinical Study


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